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chicago, IL

Does tretinoin cause wrinkles?

Another member of this board said that she met with a plastic surgeon recently who told her that retin-a causes wrinkles. I was surprised at this, so I did a search of the clinical studies available on pubmed and google scholar, but I saw only positive results related to tretinoin use, such as increased collagen production; and none of the literature I read mentions that it causes wrinkles. Could be that I found nothing because I performed the search incorrectly or such studies weren't accessible from these sites. Can any dermatologist offer any illuminating information related to this? Thank you

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beverly Hills, CA
United States
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March 15, 2012 11:17 PM

Retinoids were developed in Europe but most of the work on acne and photo aging was performed by Albert Kligman at the University Of Pennsylvania School Of Medicine's Durhing labs. (more)
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